Specification :

Docetaxel Anhydrous CAS: 114977-28-5
Molecular formula: C43H53NO14 molecular weight: 807.88
Description: This product is taxane anticancer compounds.
Pharmacological effects: mechanism of action of this product is to enhance tubulinpolymerization and inhibiting microtubule depolymerization, resulting in the formation ofstable non-functional micro-tubes, thus destroying the tumor cell mitosis. The productconcentration in the cell three times higher than paclitaxel, and long residence time in the cell, which is the product in vitro antitumor activity than paclitaxel big reason. In vivoexperiments on mice colon cancer, breast cancer, lung cancer, ovarian cancer and other effective graft. Cisplatin, etoposide, 5Fu, or paclitaxel-resistant cell line, this product does not produce cross-resistance.
Physical Properties: white or white crystalline powder; odorless. The product in DMSO ( 25mg/ ml) , ethanol ( 25mg/ ml) , dissolved in methanol, almost insoluble in water.