Specification :

Ivabradine hydrochloride(Specific inhibitor CAS:148849-67-6)
Chemical name: 3 - [3 - [[(8S) -3,4 - dimethoxy--8 - azabicyclo [4.2.0] oct -1,3,5 - triene] methyl - amino-A] propyl] -7,8 - dimethoxy-2,5 - dihydro-1H-3-aza-benzo zhuo -4 – hydrochloride
Formula C27H36N2O5 . HCl
CAS:148849-67-6
Belong to Chemical Drug line 3.1
Drug direction:
Formulations and specifications:Tablet, 5mg, 7.5mg
Indications: for patients with chronic stable angina pectoris.
Usage and dosage: usually recommended starting dose: 5mg / times, 2 times / day. Medication after 3-4 weeks, according to the treatment effect increased to 7.5mg / times, 2 times / day. If during treatment, continued to reduce the resting heart rate of less than 50 times / min, or patients who experience symptoms related to slow heart rate, such as dizziness, fatigue or low blood pressure, the dose must be adjusted downwards, including the possibility of dose of 2.5mg / times 2 times / day. If the heart rate of less than 50 times / min, bradycardia, or cardiac symptoms persist, they should stop the medication. Must be twice-daily oral administration, for example, take breakfast and dinner. Medication in elderly patients: Iraq attack mine set in a small number of 75-year-old or above study shows that elderly patients, the patient should adopt a lower starting dose, according to the need to increase dosage.
Also,we supply intermediate :
1.(1S)-4,5-dimethoxy-1-(methylaminomethyl)-benzocyclobutane hydrochloride 866783-13-3 for Ivabradine hydrochloride
2. 7,8-dimethoxy-1,3-dihydro-2H-3-Benzazepin-2-one 73942-87-7
for Ivabradine hydrochloride