Specification :

Tobramycin Base CAS: 32986-56-4e900¼ g/ mg USP33 GMP
Molecular formula: C18H37N5O9 Molecular Weight: 467.51
Description: This is a aminoglycoside antibiotics.
Pharmacological effects: tobramycin to join in the 30S and 50S of the link position, hindering the formation of 70S complexes, so that mRNA is not translated into proteins, leading to cell death. b Gentamicin antibacterial spectrum similar to, Escherichia coli, aerogenes, Klebsiella, Proteus mirabilis, some indole-positive Proteus, Pseudomonasaeruginosa, Neisseria some, a these non-pigmented Serratia spp and Shigella bacteriaGram-negative bacteria have an antibacterial effect; this product' s antibacterial activityagainst Pseudomonas aeruginosa than gentamicin 3 to 5 times stronger, moderatelysensitive to gentamicin P. Pseudomonas is highly sensitive to the chemicals. Gram-positive bacteria, Staphylococcus aureus ( including-lactamase producing strains) sensitive to the chemicals; streptococci ( including Streptococcus pyogenes, Streptococcus pneumoniae, Streptococcus faecalis, etc.) are resistant to the chemicals.Anaerobes ( Bacteroides species) , Mycobacterium tuberculosis, Rickettsia, viruses and fungi are also resistant to the chemicals.
Physical properties: White to off-white hygroscopic powder. This product is soluble in water, slightly soluble in ethanol, practically insoluble in chloroform and ether.