Specification :

Empenthrin

Common name: empenthrin; empenthrine
IUPAC name: ( E) -( RS) -1-ethynyl-2-methylpent-2-enyl ( 1R, 3RS; 1R, 3SR) -2, 2-dimethyl-3-( 2-methylprop-1-enyl) cyclopropanecarboxylate
Roth: ( E) -( RS) -1-ethynyl-2-methylpent-2-enyl ( 1R) -cis-trans-2, 2-dimethyl-3-( 2-methylprop-1-enyl) cyclopropanecarboxylate
C hemical Abstracts name: 1-ethynyl-2-methyl-2-pentenyl ( 1R) -cis-trans-2, 2-dimethyl-3-( 2-methyl-1-propenyl) cyclopropanecarboxylate
C AS RN: [ 54406-48-3] unstated stereochemistry
EEC no.: 259-154-4

PHYSICAL CHEMISTRY
Composition: The name empenthrin is defined for the ( E) -( RS) ( 1RS) -cis-trans- mixed isomers. However, the material in use is the ( EZ) -( RS) ( 1R) - rich cis-trans- isomer mixture. Mol. wt.: 274.4; M.f.: C18H26O2. Form: Yellow liquid. B.p.: 295.5 º C/ 760 mmHg. V.p.: 14 mPa ( 23.6 º C) . S.g./ density: 0.927 ( 20 º C) . Solubility: In water 0.111 mg/ l ( 25 º C) . Totally miscible in hexane, acetone and methanol ( 20 º C) . Stability: Stable under normal conditions for at least 2 years. F.p.: 107 ° C.

APPLICATIONS
Mode of action: Insecticide with contact action. Compared with other pyrethroids, has a high vapour pressure and hence is active against flying insects.
Uses: Used as a domestic insecticide, especially against moths, woolly bears and other insects attacking fabrics.
Formulation types: Aerosol; Impregnated material.
Compatibility: Not compatible with alkaline materials.

MAMMALIAN TOXICOLOGY
Oral: Acute oral LD50 for male rats > 5000, female rats > 3500 mg/ kg.
Skin and eye: Acute percutaneous LD50 for rats > 2000 mg/ kg. Not irritating to skin; minimal irritation to eyes ( rabbits) .
Inhalation: LC50 ( 4 h) for rats > 4610 mg/ m3.
Toxicity class: WHO ( a.i.) III

ECOTOXICOLOGY
Birds: Acute oral LD50 for bobwhite quail and mallard ducks > 2250 mg/ kg. Dietary LC50 for bobwhite quail and mallard ducks > 5620 ppm.
Fish: LC50 ( 96 h) for rainbow trout 0.0017 mg/ l.
Daphnia EC50 ( 48 h) 0.02 mg/ l.