Specification :

Delivery: Express courier.
The min. order is 10 grams.
keyword: steroid hormones, APIs, progestogen, estrogen
CAS: 56-53-1
MF: C18H20O2
MW: 268.35
EINECS: 200-278-5
Product Categories: Miscellaneous Biochemicals; Intermediates & Fine Chemicals; Pharmaceuticals
Mol File: 56-53-1.mol
mp 170-172 ° C( lit.)
storage temp. 0-6° C
solubility methanol: 0.1 g/ mL, clear, faintly yellow
Water Solubility PRACTICALLY INSOLUBLE
Hazard Codes T, N
Risk Statements 45-61-36/ 37/ 38-51/ 53-40
Safety Statements 53-36/ 37/ 39-45-60-61
RTECS WJ5600000
HazardClass 6.1( b)
PackingGroup III
Chemical Properties White Solid
Usage A synthetic, nonsteroidal estrogen. Recomended solvents are DMSO, DMF and ethanol, even in these solvents do not store in solution for any prolonged period of time.
General Description Odorless tasteless white crystalline powder.
Air & Water Reactions Insoluble in water.
Reactivity Profile Diethylstilbestrol is incompatible with strong oxidizing agents, strong bases, acid chlorides and acid anhydrides .
Fire Hazard Flash point data for Diethylstilbestrol are not available; however, Diethylstilbestrol is probably combustible.
Raw materials 1, 4-Dioxane--> Formamide
Diethylstilbestrol ( DES, former BAN stilboestrol) is a synthetic nonsteroidal estrogen that was first synthesized in 1938. Human exposure to DES occurred through diverse sources, such as dietary ingestion from supplemented cattle feed and medical treatment for certain conditions, including breast and prostate cancers. From about 1940 to 1970, DES was given to pregnant women under the mistaken belief it would reduce the risk of pregnancy complications and losses. In 1971, DES was shown to cause a rare vaginal tumor in girls and women who had been exposed to this drug in utero. The United States Food and Drug Administration subsequently withdrew DES from use in pregnant women. Follow-up studies have indicated that DES also has the potential to cause a variety of significant adverse medical complication during the lifetime of those exposed.[ 1] The United States National Cancer Institute recommends[ 2] that women born to mothers who took DES undergo special medical exams on a regular basis to screen for complications as a result of the drug. Women exposed to DES are commonly referred to as " DES daughters" .
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