Specification :

Kojic Acid

CTFA name: 5-hydroxy-2-hydroxymethyl-1, 4-pyrone
INCI Name: Kojic Acid
EINECS No.: 207-922-4
CAS no: 501-30-4
HS code: 2932 9990.99
Molecular l Formula: C6H6O4
Molecular weight: 142.1
Toxicity: LD502500-3500mg/ kg
Dissolving water, alcohol, acetone and slightly dissolving ether second ester of second acid, chloroform and pyridine, non-dissolving benzene.

Specification
Appearance: White Crystal or Powder
Assay: 99.0% min
Melting Point: 152-155 deg. C
Loss on Drying: 0.5% max
Residue on Ignition: 0.1% max
Chloride: 0.005% max
Heavy Metals: 0.001% max
Iron: 0.001% max
Arsenic: 0.0001% max
Microbiological Test:
Bacteria: 3000CFU/ g max
Fungi: 50CFU/ g max
Colon bacillus: Negative

Packing in carton, inner sealed with 1kg, 1kg* 5, 1kg* 10 aluminized plastic bag.
Packing in cardboard drum, inner sealed with 25kg aluminized plastic bag.

Storage out of sunlight, sealed for two years.

Application
1) Daily chemicals material: Because Kojic Acid can inhibits caseinase synthesis, then inhibits skin melanin formation, Kojic Acid and it' s derivatives are widely used in high-quality brightening cosmetic, bath cream, and toothpaste. The products containing kojic acid can treat freckle, acne, pigmentation and macula effectively without any toxic and bad results. At present, the use level of Kojic Acid added in cosmetic amounts to 0.5% -2% .
2) Medicine material: Kojic Acid and its derivatives are used as an important material in antibiotic - cethamycin, anodyne, and antichloristic production.
3) Food additive: Kojic Acid and its derivatives work as antiseptic, antioxidant, preservative and color stabilizer in meat processing, also act as useful materials of food aromatizer-maltol and ethyimaltol.
4) Preservative and color stabilizer of cut-flower: Kojic Acid and its derivatives are added to cub-flower to keep the flower colorful and fresh.
Kojic Acid is one of the most successful recent and natural skin whitening agents . It act as Tyrosinase inhibitors, similar to Arbutin which inactivate Tyrosinase by chelating with its vital cooper ion and suppressing the tautomerization from dopa chrome to DHICA, it also act as reducing agents on melanin intermediates, thus blocking the oxidation chain reaction at various points from tyrosine/ DOPA to melanin. This property of Kojic acid has led to its use in cosmetics formulation for helping de-pigmentation of the skin including whitening age spots and hyper pigmentation ( brown spotting) . Kojic acid also has mild antibiotic properties.
As skin whitening antiaging and lightening agents.
As plant growth-regulating agents.
As discoloration prevention agents of vegetables and foods.
As intermediate in synthesis.