Specification :

Kojic Acid Dipalmitate

CTFA Name: Kojic Acid Dipalmitate
INCI Name: Kojic Dipalmitate
Alternate names: KAD-15
Chemical Name: 2-palmitoyloxymethyl-5-palmitoyloxy- r- pyrone
CAS no: 79725-98-7
Molecular weight: 618.9
Molecular formula: C38H66O6
HS Code: 2915 7090
Solubility soluble in ware alcohol, mineral oil and esters

Specification
Appearance: White sheet crystals
Assay: 98% min
Melting point: 92-96 Deg. C
Loss on drying: 0.5% max
Residue on Ignition: 0.5% max
Heavy Metals: 0.001% max
Arsenic: 0.0002% max
Color Reaction of Ferric Chloride: Negative
Microbiological Test:
Bacteria: 300CFU/ g max
Fungi: 100CFU/ g max

Packing in carton, inner sealed with 1kg aluminized plastic bag.
Packing in cardboard drum, inner sealed with 1kg x 20 aluminized plastic bag.

Storage out of sunlight, sealed for two years.

Application
Kojic Acid Dipalmitate is modified kojic acid derivative, which not only overcomes the instability to light, heat and metallic ion, but also keeps activity of the inhibitory tyrosine and prevents the forming of melanin.
Kojic Acid Dipalmitate has an excellent property of inhibiting the activity of tyrosinase present in the human skin so as to inhibit the melanin formation.It is more efficacious than straight kojic acid. Kojic Acid Dipalmitate can produce excellent effects in even toning the skin, fighting age spots, pregnancy marks, freckles as well as general skin pigmentation disorders of face and body. Unlike kojic acid, which often causes product stability problems such as color changes, Kojic Acid Dipalmitate offers excellent product stability without any color instability problems.
1. Skin Lightening. Kojic Acid Dipalmitate offers more efficacious skin lightening effects. Compared with kojic acid, Kojic Acid Dipalmitate markedly enhances the inhibitory effects on tyrosinase activity, which prohibits the formation of melanin.
2. Light and Heat Stability. Kojic Acid Dipalmitate is light and heat stable, while kojic acid tends to oxidize over time.
3. pH Stability: Kojic Acid Dipalmitate is stable within a wide pH range of 4-9, which provides flexibility to formulators.
4. Color Stability. Unlike kojic acid, Kojic Acid Dipalmitate does not turn brown or yellow over time for two reasons.First, kojic acid is not stable to light and heat, and tends to oxidize, which results in color change ( often yellow or brown) . Second, kojic acid tends to chelate with metal ions ( e.g. iron) , which often results in color change.On the contrary, Kojic Acid Dipalmitate is stable to pH, light, heat and oxidation, and does not complex with metal ions, which lead to color stability.
Applications: Skin care, sun care, skin whitening/ lightening, treatment for pigmentary disorders such as age spots etc.
Use level Skin care products: 1-5%