Genistein Original Plant: Seed of Sophora japonica L. Synonyms: CI 75610; Genestein; genisteol; genisterin; prunetol; sophoricol Chemical Name: 4' , 5, 7-trihydroxyisoflavone 5, 7-dihydroxy-3-( 4-hydroxyphenyl) -4H-1-benzopyra n-4-one Specification: 98% Test Method: HPLC Molecular Formula: C15H10O5 Molecular Weight: 270.23 CAS No.: 529-59-9 Melting point: 297--298C Solubility: Soluble in DMSO and Ethanol, hardly dissolve in water. Pharmacology Action: Genistein binds to and inhibits protein-tyrosine kinase, thereby disrupting signal transduction and inducing cell differentiation. This agent also inhibits topoisomerase-II, leading to DNA fragmentation and apoptosis, and induces G2/ M cell cycle arrest. Genistein exhibits antioxidant, antiangiogenic, and immunosuppressive activities.