The active ingredient in Oxycontin is Oxycodone which is the main ingredient in Percocet, Percodan, Tylox, Roxicet, Oxycocet, OxyIR, Endodan, Endocet and probably a few more names not mentioned. Oxycodone has been around for years and is used for moderate to severe pain. It is a Schedule II controlled substance. It works by inhibiting ascending pain pathways in the Central Nervous System, increases the pain threshold, and alters pain perception