corosolic acid

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Origin:

China

Corosolic acid

Source: loquat, or Lagerstroemia speciosa ( commonly known as Barnabas, abound in the Philippines Islands) extract.

1, ( corosolic acid) , 2± -hydroxy-ursolic acid ( 2-alpha-hydroxyursolic acid) , product name: plant insulin.

2, Molecular Formula: C30H48O4

3, CAS No : 4547-24-4

4, pharmacological effects: experimental results show that, in order to achieve its hypoglycemic effect corosolic acid transport through the excitement of glucose to promote cellular glucose uptake and utilization. on glucose transport corosolic acid is similar to the stimulation of insulin, so, corosolic acid is also known as plant insulin. Animal experiments showed that corosolic acid has significant hypoglycemic effect in normal rats and hereditary diabetic mice showed. Corosolic acid also has weight-loss effects, clinical study found that after taking the drug it will be able to adjust insulin and blood glucose levels, with significant weight loss trend ( the average monthly weight loss 0.908-1.816Kg) , the process is slow and without dieting. corosolic acid also has many other biological activities, such as the inflammatory response induced by TPA has significant inhibition effect, its anti-inflammatory effect is stronger than commercially available anti-inflammatory drug indomethacin; It also has a DNA polymerase inhibition activity, as well as inhibit the growth of various cancer cell lines.

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