Specification :

ITC01: Irinotecan

7-Ethyl-10-[ 4-( 1-piperidino) -1-piperidino] carbonyloxycamptotheci n;
( + ) -( 4S) -4, 11-diethyl-4-hydroxy-9-[ ( 4-piperidinopiperidino) carbonyloxy] -1 H-pyrano[ 3' , 4' : 6, 7] indolizino[ 1, 2-b] quinoline-3, 14-( 4H, 12H) -dione.

[ CAS # 97682-44-5]

ITC02: Irinotecan Hydrochloride Trihydrate

7-Ethyl-10-[ 4-( 1-piperidino) -1-piperidino] carbonyloxycamptotheci n Hydrochloride Trihydrate
[ CAS # 136572-09-3]

ITC03: Irinotecan Acid Sodium Salt

7-Ethyl-10-[ 4-( 1-piperidino) -1-piperidino] carbonyloxycamptothecin Acid Sodium Salt

ITC04: Irinotecan 12-Hydroxy Impurity

( 4S) -4, 11-Diethyl-4, 12-dihydroxy-9-[ ( 4-piperidinopiperidino) carbon yloxy] -1H-pyrano[ 3’ , 4’ : 6, 7] indolizino[ 1, 2-b] quinoline-3, 14( 4H, 12H) -dione ( " 12-Hydroxy Irinotecan " )
[ CAS # 185336-12-3]

ITC05: Irinotecan 2-Hydroxy Impurity

( 4S) -4, 11-Diethyl-4-hydroxy-9-[ ( 2-hydroxy-4-piperidinopiperidino) c arbonyloxy] -1H-pyrano[ 3’ , 4’ : 6, 7] indolizino[ 1, 2-b] -quinoline-3, 14( 4H, 12H) -dio ne ( " 2-Hydroxy Irinotecan " )

ITC06: Irinotecan Lactone Impurity

3, 10-diethyl-8-[ ( 4-piperidinopiperidino) carbonyloxy] furo[ 3’ , 4’ : 6, 7 ] indolizino[ 1, 2-b] quinoline-1, 13( 3H, 11H) -dione
[ CAS # 143490-53-3]

ITC07: Irinotecan Descarbonyl Impurity

3, 10-Diethyl-1, 3-dihydro-3-hydroxy-8-[ ( 4-piperidinopiperidino) carb onyloxy] furo[ 3’ , 4’ : 6, 7] indolizino[ 1, 2-b] quinoline-13-( 11H ) -one

ITC08: Irinotecan Keto Impurity

10-Ethyl-2-methyl-3-propionyl-8-[ ( 4-piperidinopiperidino) carbonylo xy] indolizino[ 1, 2-b] quinoline-1-( 11H ) -one