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Adderall is a brand-name pharmaceutical psychostimulant composed of mixed amphetamine salts. The drug is used primarily to treat attention-deficit hyperactivity disorder and narcolepsy. Adderall has also been used successfully to manage severe cases of treatment-resistant depression. Individuals who show little or no response to typical antidepressants--such as the SSRIs and tricyclics--are more likely to respond to psychostimulant therapy. These patients, however, are the exception, rather than the norm amongst depression patients.

Adderall’ s inclusion of levoamphetamine provides the pharmaceutical with a quicker onset and longer clinical effect compared to pharmaceuticals exclusively formulated of dextroamphetamine. Although it seems that where the human brain has a preference for dextroamphetamine over levoamphetamine, it has been reported that certain children have a better clinical response to levoamphetamine.

Specifically, Adderall XR is composed of the following proportions of active ingredients:
- 1/ 4 dextroamphetamine saccharate
- 1/ 4 dextroamphetamine sulfate
- 1/ 4 ( racemic dextro/ laevo-amphetamine) aspartate monohydrate
- 1/ 4 ( racemic dextro/ laevo-amphetamine) sulfate