Specification :

A topoismerase I antagonist. Topotecan Hydrochloride, with a strong antineoplastic activity and a wide anticancer spectrum, is the best therapy for ovarian cancer and is also clinically involved in therapy for breast carcinoma, rectal cancer, colon carcinoma and acute or chronic leukemia.
CURRENT STATUS: Topotecan Hydrochloride produced in CREDIT CHEMWERTH, with an assay content of NLT 99.5% and single largest impurity of NMT 0.1%, is anticipating for FDA¡¯s inspection for cGMP compliance, and CREDIT CHEMWRTH already had the DMF filed.