Alpha-Arbutin(±-Arbutin) ±-Arbutin(Alpha Arbutin) is a new type of hydroquinone glucoside with an ±-glucosyl bond. as a skin-lightening ingredient of cosmetics, ±-Arbutin has strong inhibiting effect on human tyrosinase. Indeed, the enzyme is involved in synthesis of melanin which causes freckles and suntan. ±-Arbutin is a cosmetic ingredient that customers can use safely and comfortably. For your use of ±-Arbutin, you can receive not only quality assurance but also data concerning safety and efficacy as well as support with respect to ±-Arbutin-related applications. Mechanism of Melanogenesis Inhibition of ±-Arbutin: ±-Arbutin and ²- Arbutin: Sample Mushroom Human IC50 IC50 ±-Arbutin Not detected 1.8 - 2.1 mM Arbutin (²) 8 mM > 30 mM Trade Name ±-Arbutin Chemical name 4-Hydroxyphenyl-±-D-glucopyranoside CAS No. 84380-01-8 ELINCS No. 440-470-8 INCI name Alpha-Arbutin Molecular Formula C12H16O7 Molecular Weight 272.25 Chemical Structure Specifications Appearance White powder Purity e99% HPLC Melting point 196 ~ 202°C Specific rotation [±]20D +180±6° Solution Clear Loss on drying Less than 1.0% Microbiological Specified pathogens None Microbial count d100 CFU/g Fungus d50 CFU/g Safety To be safe for cosmetic use. The available data do not indicate any risks. Storage ±-Arbutin (Alpha-Arbutin) should be stored in the original sealed pouchs protected from light and humidity in a clean area at a temperature of between 10 and 30°C. If stored under the recommended conditions, ±-Arbutin remains stable for 3 years. Packing 1kg PVC+aluminum pouch