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PKI587
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ABT-888
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Technical Data:
M.Wt: 244.0
Formula: C13H16N4O
Solubility: Soluble in water or DMSO
Purity: 99%
Storage: -20C 2 years
CAS No: 912444-00-9
Biological Activity:
Potent inhibitor of PARP-1 and PARP-2 ( potency 97% suitable for in vivo studies. Does not show inherent cytotoxicity and shows no single agent activity in tumor models. Has excellent bioavailability and good blood-brain permeation. Increases tumor growth delay resulting from radiation and DNA-damaging agents.
E-mail : orders@ biochempartner.com
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