Grape Seed Extract

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What It Is Used For
Grape seed extract is used for conditions related to the heart and blood vessels, such as atherosclerosis (hardening of the arteries), high blood pressure, high cholesterol, and poor circulation.
Other reasons for the use of grape seed extract include complications related to diabetes, such as nerve and eye damage; vision problems, such as macular degeneration (which can cause blindness); and swelling after an injury or surgery.
Grape seed extract is also used for cancer prevention and wound healing.
What the Science Says
Laboratory studies have shown that grape seed contains antioxidants-substances that prevent cell damage caused by free radicals, which are highly reactive molecules that can damage cell function. However, it is still unclear how grape seed might affect human health.
Grape seed extracts have shown some beneficial antioxidant effects in preliminary clinical trials. However, few trials have looked at specific diseases or conditions, and little scientific evidence is available.
A study funded by the National Cancer Institute (NCI) found that grape seed extract did not reduce the hardening of breast tissue that can occur after radiation therapy for breast cancer.
NCI is also funding studies evaluating whether grape seed extract is effective in preventing breast and prostate cancers.
NCCAM is studying whether the action of grape seed extract and its components may benefit the heart or have protective effects in the brain.

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