Phellodendron chinese Extract Berberine Chloride Hydrastis canadensis goldenseal

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Phellodendron chinese Extract Berberine Chloride Hydrastis canadensis goldenseal
Phellodendron chinese Extract Berberine Chloride Hydrastis canadensis goldenseal
Berberine
Introduction
Berberine is a plant alkaloid with a long history
of medicinal use in both Ayurvedic and Chinese
medicine. It is present in Hydrastis canadensis
(goldenseal), Coptis chinensis (Coptis or goldenthread), Berberis aquifolium (Oregon grape), Berberis vulgaris
(barberry), and Berberis aristata (tree turmeric). The berberine alkaloid can be found in the roots, rhizomes, and
stem bark of the plants. Berberine extracts and decoctions have demonstrated significant antimicrobial activity
against a variety of organisms including bacteria, viruses, fungi, protozoans, helminths, and chlamydia. Currently,
the predominant clinical uses of berberine include bacterial diarrhea, intestinal parasite infections, and
ocular trachoma infections.
Pharmacology
The pharmacologic actions of berberine include metabolic inhibition of certain organisms, inhibition of
bacterial enterotoxin formation, inhibition of intestinal fluid accumulation and ion secretion, inhibition of smooth
muscle contraction, reduction of inflammation, platelet aggregation inhibition, platelet count elevation in certain
types of thrombocytopenia, stimulation of bile and bilirubin secretion, and inhibition of ventricular
tachyarrhythmias.1,2

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