NewEast Biosciences

http://indomonster.com/neweastbiosciences

NewEast Biosciences are specialized in generating protein configuration-specific monoclonal antibodies that recognize active ( GTP-bound) G proteins ( including Ras-superfamily small GTPases and heterotrimeric G proteins) . These unique antibodies do not recognize the inactive ( GDP-bound) G proteins. These monoclonal antibodies have been successfully used to immunoprecipitate active G proteins from cell lysates, and for immunohistochemical staining of active G proteins in cultured cells or in tissue sections. Hence, these antibodies can be used to study the spatial and temporal dynamics of cellular signaling involving big and small G proteins, the future direction of signal transduction studies.

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